No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
11718 |
4. Check minimum number of eventsNone |
11718 |
5. Include endpoints |
12163 |
6. Filter based on genotype QC (FinnGen only) |
11784 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D10-D36
Name in latin
Naevi melanocytici
Similar endpoints
↥List of similar endpoints to
Melanocytic naevi
based on the number of shared cases.
Similar with more cases:
- Melanocytic naevi
- Benign neoplasms
- Benign neoplasms
- Neoplasms
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 88627 | 53433 | 34898 |
| Only index persons | 83857 | 51178 | 32679 |
| Unadjusted period prevalence (%) | |||
| Whole population | 1.31 | 1.53 | 0.98 |
| Only index persons | 1.63 | 1.88 | 1.25 |
| Median age at first event (years) | |||
| Whole population | 43.66 | 42.40 | 45.59 |
| Only index persons | 44.06 | 42.70 | 46.18 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 11784 | 7681 | 4103 |
| Unadjusted period prevalence (%) | 2.68 | 3.02 | 2.06 |
| Median age at first event (years) | 50.98 | 46.61 | 59.16 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_MELANOCYTIC and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_MELANOCYTIC | 0.957 [0.86, 1.06] | 0.418 |
| Birth year | 0.995 [0.99, 1.0] | 0.226 |
During the follow-up period (1.1.1998 — 31.12.2019), 2689 out of 38766 females with CD2_BENIGN_MELANOCYTIC died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_MELANOCYTIC | 0.961 [0.86, 1.07] | 0.464 |
| Birth year | 0.989 [0.98, 1.0] | 0.015 |
During the follow-up period (1.1.1998 — 31.12.2019), 3060 out of 26073 males with CD2_BENIGN_MELANOCYTIC died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_MELANOCYTIC.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.083% | 0.17% |
| 5 | 0.555% | 1.067% |
| 10 | 1.39% | 2.926% |
| 15 | 2.67% | 5.548% |
| 20 | 4.581% | 9.281% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_MELANOCYTIC – Melanocytic naevi
GWS hits: 9
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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