No definition available.
Melanocytic naevi of eyelid, including canthus
EFO MESH Endpoint Browser PheWeb
CD2_BENIGN_MELANOCYTIC_EYELID
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
297 |
4. Check minimum number of eventsNone |
297 |
5. Include endpointsNone |
297 |
6. Filter based on genotype QC (FinnGen only) |
291 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D22
Name in latin
Naevus melanocyticus palpebrae
Similar endpoints
↥List of similar endpoints to
Melanocytic naevi of eyelid, including canthus
based on the number of shared cases.
Similar with more cases:
- Melanocytic naevi of eyelid, including canthus
- Melanocytic naevi
- Melanocytic naevi
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2724 | 1781 | 930 |
| Only index persons | 2569 | 1697 | 872 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.05 | 0.03 |
| Only index persons | 0.05 | 0.06 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 53.01 | 52.48 | 53.88 |
| Only index persons | 52.34 | 51.73 | 53.51 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 291 | 200 | 91 |
| Unadjusted period prevalence (%) | 0.07 | 0.08 | 0.05 |
| Median age at first event (years) | 53.32 | 49.87 | 60.92 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_MELANOCYTIC_EYELID and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_MELANOCYTIC_EYELID | 1.0 [0.84, 1.19] | 0.997 |
| Birth year | 0.992 [0.98, 1.0] | 0.082 |
During the follow-up period (1.1.1998 — 31.12.2019), 204 out of 1551 females with CD2_BENIGN_MELANOCYTIC_EYELID died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_MELANOCYTIC_EYELID | 0.878 [0.71, 1.08] | 0.225 |
| Birth year | 0.99 [0.98, 1.0] | 0.034 |
During the follow-up period (1.1.1998 — 31.12.2019), 131 out of 811 males with CD2_BENIGN_MELANOCYTIC_EYELID died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_MELANOCYTIC_EYELID.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.089% | 0.209% |
| 5 | 0.526% | 0.992% |
| 10 | 1.281% | 2.568% |
| 15 | 2.448% | 5.089% |
| 20 | 4.458% | 8.86% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_MELANOCYTIC_EYELID – Melanocytic naevi of eyelid, including canthus
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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