No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
291 |
4. Check minimum number of eventsNone |
291 |
5. Include endpointsNone |
291 |
6. Filter based on genotype QC (FinnGen only) |
283 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D22
Name in latin
Naevus melanocyticus (cutis) labii (oris)
Melanocytic naevi of lip
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2143 | 1358 | 781 |
| Only index persons | 2030 | 1302 | 728 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.03 | 0.04 | 0.02 |
| Only index persons | 0.04 | 0.05 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 39.45 | 40.56 | 37.57 |
| Only index persons | 38.35 | 40.23 | 35.00 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 283 | 212 | 71 |
| Unadjusted period prevalence (%) | 0.07 | 0.08 | 0.04 |
| Median age at first event (years) | 44.95 | 43.55 | 49.11 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_MELANOCYTIC_LIP and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_MELANOCYTIC_LIP | 0.855 [0.68, 1.07] | 0.173 |
| Birth year | 1.0 [0.99, 1.01] | 0.977 |
During the follow-up period (1.1.1998 — 31.12.2019), 98 out of 1211 females with CD2_BENIGN_MELANOCYTIC_LIP died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_MELANOCYTIC_LIP | 1.024 [0.79, 1.32] | 0.855 |
| Birth year | 0.988 [0.98, 1.0] | 0.015 |
During the follow-up period (1.1.1998 — 31.12.2019), 99 out of 689 males with CD2_BENIGN_MELANOCYTIC_LIP died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_MELANOCYTIC_LIP.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.102% | 0.184% |
| 5 | 0.639% | 1.242% |
| 10 | 1.545% | 3.197% |
| 15 | 2.804% | 5.88% |
| 20 | 4.939% | 10.045% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_MELANOCYTIC_LIP – Melanocytic naevi of lip
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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