brain neoplasm: A neoplasm (disease) that involves the brain.
Melanocytic naevi of scalp and neck
DOID EFO Endpoint Browser PheWeb
CD2_BENIGN_MELANOCYTIC_SCALPNECK
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
803 |
4. Check minimum number of eventsNone |
803 |
5. Include endpointsNone |
803 |
6. Filter based on genotype QC (FinnGen only) |
779 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D22
Name in latin
Naevus melanocyticus (cutis) verticis cranii
Similar endpoints
↥List of similar endpoints to
Melanocytic naevi of scalp and neck
based on the number of shared cases.
Similar with more cases:
- Melanocytic naevi of scalp and neck
- Melanocytic naevi
- Melanocytic naevi
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 6814 | 3784 | 3011 |
| Only index persons | 6315 | 3553 | 2762 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.10 | 0.11 | 0.08 |
| Only index persons | 0.12 | 0.13 | 0.11 |
| Median age at first event (years) | |||
| Whole population | 35.03 | 34.26 | 35.95 |
| Only index persons | 36.18 | 35.14 | 37.52 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 779 | 473 | 306 |
| Unadjusted period prevalence (%) | 0.17 | 0.19 | 0.15 |
| Median age at first event (years) | 47.68 | 42.04 | 56.39 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_MELANOCYTIC_SCALPNECK and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_MELANOCYTIC_SCALPNECK | 0.786 [0.65, 0.95] | 0.011 |
| Birth year | 0.992 [0.98, 1.0] | 0.06 |
During the follow-up period (1.1.1998 — 31.12.2019), 169 out of 3036 females with CD2_BENIGN_MELANOCYTIC_SCALPNECK died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_MELANOCYTIC_SCALPNECK | 1.089 [0.92, 1.3] | 0.336 |
| Birth year | 0.983 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 295 out of 2431 males with CD2_BENIGN_MELANOCYTIC_SCALPNECK died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_MELANOCYTIC_SCALPNECK.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.068% | 0.168% |
| 5 | 0.421% | 1.092% |
| 10 | 1.019% | 2.71% |
| 15 | 1.971% | 5.418% |
| 20 | 3.539% | 9.434% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_MELANOCYTIC_SCALPNECK – Melanocytic naevi of scalp and neck
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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