No definition available.
Melanocytic naevi of lower limb, including hip
EFO MESH Endpoint Browser PheWeb
CD2_BENIGN_MELANOCYTIC_LOWERLIMB
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1428 |
4. Check minimum number of eventsNone |
1428 |
5. Include endpointsNone |
1428 |
6. Filter based on genotype QC (FinnGen only) |
1391 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D22
Name in latin
Naevus melanocyticus (cutis) coxae
Similar endpoints
↥List of similar endpoints to
Melanocytic naevi of lower limb, including hip
based on the number of shared cases.
Similar with more cases:
- Melanocytic naevi of lower limb, including hip
- Melanocytic naevi
- Melanocytic naevi
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 10634 | 6739 | 3862 |
| Only index persons | 9877 | 6347 | 3530 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.16 | 0.19 | 0.11 |
| Only index persons | 0.20 | 0.23 | 0.13 |
| Median age at first event (years) | |||
| Whole population | 39.83 | 41.13 | 37.49 |
| Only index persons | 41.39 | 42.30 | 39.75 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1391 | 967 | 424 |
| Unadjusted period prevalence (%) | 0.33 | 0.38 | 0.21 |
| Median age at first event (years) | 50.86 | 47.66 | 58.16 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_MELANOCYTIC_LOWERLIMB and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_MELANOCYTIC_LOWERLIMB | 1.071 [0.91, 1.27] | 0.422 |
| Birth year | 0.999 [0.99, 1.01] | 0.838 |
During the follow-up period (1.1.1998 — 31.12.2019), 287 out of 5208 females with CD2_BENIGN_MELANOCYTIC_LOWERLIMB died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_MELANOCYTIC_LOWERLIMB | 0.987 [0.82, 1.19] | 0.889 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 228 out of 2989 males with CD2_BENIGN_MELANOCYTIC_LOWERLIMB died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_MELANOCYTIC_LOWERLIMB.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.098% | 0.19% |
| 5 | 0.626% | 1.261% |
| 10 | 1.676% | 2.956% |
| 15 | 3.351% | 5.426% |
| 20 | 6.121% | 9.002% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_MELANOCYTIC_LOWERLIMB – Melanocytic naevi of lower limb, including hip
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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