brain neoplasm: A neoplasm (disease) that involves the brain.
Melanocytic naevi of upper limb, including shoulder
DOID EFO Endpoint Browser PheWeb
CD2_BENIGN_MELANOCYTIC_UPPERLIMB
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
741 |
4. Check minimum number of eventsNone |
741 |
5. Include endpointsNone |
741 |
6. Filter based on genotype QC (FinnGen only) |
710 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D22
Name in latin
Naevus melanocyticus (cutis) regionis deltoideae
Similar endpoints
↥List of similar endpoints to
Melanocytic naevi of upper limb, including shoulder
based on the number of shared cases.
Similar with more cases:
- Melanocytic naevi of upper limb, including shoulder
- Melanocytic naevi
- Melanocytic naevi
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5751 | 3429 | 2304 |
| Only index persons | 5400 | 3265 | 2135 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.08 | 0.10 | 0.06 |
| Only index persons | 0.10 | 0.12 | 0.08 |
| Median age at first event (years) | |||
| Whole population | 41.00 | 39.84 | 42.75 |
| Only index persons | 41.93 | 40.42 | 44.24 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 710 | 468 | 242 |
| Unadjusted period prevalence (%) | 0.16 | 0.18 | 0.12 |
| Median age at first event (years) | 52.47 | 48.25 | 60.63 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_MELANOCYTIC_UPPERLIMB and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_MELANOCYTIC_UPPERLIMB | 0.956 [0.77, 1.18] | 0.675 |
| Birth year | 0.993 [0.98, 1.0] | 0.108 |
During the follow-up period (1.1.1998 — 31.12.2019), 141 out of 2628 females with CD2_BENIGN_MELANOCYTIC_UPPERLIMB died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_MELANOCYTIC_UPPERLIMB | 1.079 [0.87, 1.33] | 0.484 |
| Birth year | 0.986 [0.98, 1.0] | 0.005 |
During the follow-up period (1.1.1998 — 31.12.2019), 195 out of 1808 males with CD2_BENIGN_MELANOCYTIC_UPPERLIMB died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_MELANOCYTIC_UPPERLIMB.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.078% | 0.197% |
| 5 | 0.423% | 1.251% |
| 10 | 1.2% | 3.089% |
| 15 | 2.353% | 6.013% |
| 20 | 4.284% | 10.315% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_MELANOCYTIC_UPPERLIMB – Melanocytic naevi of upper limb, including shoulder
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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