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Radiation-related disorders of the skin and subcutaneous tissue

L12_RADIATIONRELATEDSKIN

phototoxic dermatitis: a form of allergic contact dermatitis in which the allergen must be activated by light to sensitize the allergic response, and to cause a rash or other systemic effects on subsequent exposure. The second and subsequent exposures produce photoallergic skin conditions which are often eczematous. In rare cases the victims die.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 L55-L59
  • Cause of death: ICD-10 L55-L59

2 out of 7 registries used, show all original rules.

15214

4. Check minimum number of events

None

15214

5. Include endpoints

15836

6. Filter based on genotype QC (FinnGen only)

15364

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Radiation-related disorders of the skin and subcutaneous tissue based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 15364 8012 7352
Unadjusted period prevalence (%) 3.41 3.15 3.69
Median age at first event (years) 71.61 70.39 72.94

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: L12_RADIATIONRELATEDSKIN – Radiation-related disorders of the skin and subcutaneous tissue

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).