No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
|
1. Apply sex-specific ruleNone |
- |
2. Check conditionsNone |
|
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
- |
4. Check minimum number of eventsNone |
- |
5. Include endpointsNone |
- |
6. Filter based on genotype QC (FinnGen only)None |
- |
Control definitions (FinnGen only)
Control exclude
C3_CANCER, C3_CANCER_WIDE
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF9
Similar endpoints
↥List of similar endpoints to
Basal cell carcinoma
based on the number of shared cases.
Similar with more cases:
- Basal cell carcinoma
- Basal cell carcinoma, including avohilmo
- Basal cell carcinoma, including avohilmo
- Malignant neoplasm, wide definition for exclusion
- Malignant neoplasm, wide definition for exclusion
Similar with less cases:
Case counts by codes
↥FinnGen case counts by registry codes:
No upset plot: script not run.
No upset table: script not run.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 118413 | 62889 | 54998 |
| Only index persons | 109216 | 58703 | 50513 |
| Unadjusted period prevalence (%) | |||
| Whole population | 1.67 | 1.80 | 1.54 |
| Only index persons | 2.05 | 2.16 | 1.93 |
| Median age at first event (years) | |||
| Whole population | 74.26 | 74.77 | 73.68 |
| Only index persons | 73.89 | 74.32 | 73.38 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 23424 | 11278 | 12146 |
| Unadjusted period prevalence (%) | 5.30 | 4.43 | 6.10 |
| Median age at first event (years) | 68.32 | 66.88 | 69.66 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint C3_BASAL_CELL_CARCINOMA_EXALLC and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| C3_BASAL_CELL_CARCINOMA_EXALLC | 0.919 [0.84, 1.01] | 0.074 |
| Birth year | 0.994 [0.99, 1.0] | 0.117 |
During the follow-up period (1.1.1998 — 31.12.2019), 15052 out of 51754 females with C3_BASAL_CELL_CARCINOMA_EXALLC died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| C3_BASAL_CELL_CARCINOMA_EXALLC | 1.015 [0.91, 1.13] | 0.784 |
| Birth year | 0.988 [0.98, 1.0] | 0.01 |
During the follow-up period (1.1.1998 — 31.12.2019), 14626 out of 44871 males with C3_BASAL_CELL_CARCINOMA_EXALLC died.
Mortality risk
Mortality risk for people of age
years, who have C3_BASAL_CELL_CARCINOMA_EXALLC.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.087% | 0.219% |
| 5 | 0.499% | 1.238% |
| 10 | 1.224% | 3.102% |
| 15 | 2.359% | 5.837% |
| 20 | 4.173% | 9.814% |
Relationships between endpoints
↥Index endpoint: C3_BASAL_CELL_CARCINOMA_EXALLC – Basal cell carcinoma
GWS hits: 88
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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