No definition available.
Behavioural syndromes associated with physiological disturbances and physical factors
EFO MESH Endpoint Browser PheWeb
F5_BEHAVE
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
14147 |
6. Filter based on genotype QC (FinnGen only) |
13531 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Behavioural syndromes associated with physiological disturbances and physical factors
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Case counts by codes
↥FinnGen case counts by registry codes:
No data for upset plot.
No data for upset table.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 132456 | 80403 | 51212 |
| Only index persons | 118006 | 73915 | 44091 |
| Unadjusted period prevalence (%) | |||
| Whole population | 1.96 | 2.30 | 1.43 |
| Only index persons | 2.33 | 2.72 | 1.68 |
| Median age at first event (years) | |||
| Whole population | 31.59 | 27.76 | 37.42 |
| Only index persons | 30.35 | 26.81 | 36.28 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 13531 | 9184 | 4347 |
| Unadjusted period prevalence (%) | 3.15 | 3.61 | 2.18 |
| Median age at first event (years) | 38.22 | 33.67 | 47.83 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint F5_BEHAVE and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| F5_BEHAVE | 1.939 [1.69, 2.22] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.253 |
During the follow-up period (1.1.1998 — 31.12.2019), 3610 out of 54138 females with F5_BEHAVE died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| F5_BEHAVE | 2.219 [1.97, 2.5] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 4402 out of 31315 males with F5_BEHAVE died.
Mortality risk
Mortality risk for people of age
years, who have F5_BEHAVE.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.206% | 0.434% |
| 5 | 1.168% | 2.489% |
| 10 | 2.808% | 6.508% |
| 15 | 5.371% | 11.959% |
| 20 | 9.394% | 19.807% |
Relationships between endpoints
↥Index endpoint: F5_BEHAVE – Behavioural syndromes associated with physiological disturbances and physical factors
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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