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Crohn's disease patients in KELA-register (KELA code 209, or 208 with ICD K50)

K11_KELACROHN

Crohn's disease: A gastrointestinal disorder characterized by chronic inflammation involving all layers of the intestinal wall, noncaseating granulomas affecting the intestinal wall and regional lymph nodes, and transmural fibrosis. Crohn disease most commonly involves the terminal ileum; the colon is the second most common site of involvement.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • KELA reimbursements: KELA codes 208
  • KELA reimbursements: ICD-10 K50

1 out of 7 registries used, show all original rules.

2490

4. Check minimum number of events

None

2490

5. Include endpoints

2490

6. Filter based on genotype QC (FinnGen only)

2396

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF3

Similar endpoints

List of similar endpoints to Crohn's disease patients in KELA-register (KELA code 209, or 208 with ICD K50) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 2396 1363 1033
Unadjusted period prevalence (%) 0.53 0.54 0.52
Median age at first event (years) 39.26 37.72 41.29

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: K11_KELACROHN – Crohn's disease patients in KELA-register (KELA code 209, or 208 with ICD K50)

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).