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Crohn disease (strict definition, require KELA)

DOID Endpoint Browser

K11_CD_STRICT

ileocolitis: Ileocolitis or ileal Crohn's is the most common type of Crohn's disease. It affects both the ileum (small intestine) and the colon.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

  • K11_KELACROHN
2490

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — K50
  • Hospital discharge: ICD-9 — 555
  • Hospital discharge: ICD-8 — 5630
  • Cause of death: ICD-10 — K50
  • Cause of death: ICD-9 — 555
  • Cause of death: ICD-8 — 5630

2 out of 7 registries used, show all original rules.

2313

4. Check minimum number of events

None

2313

5. Include endpoints

None

2313

6. Filter based on genotype QC (FinnGen only)

2227

Control definitions (FinnGen only)

Control exclude K11_CD_STRICT_PSC
Control conditions not K11_KELACROHN

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF3
Parent code in ICD-10 K50-K52
Name in latin Morbus Crohn

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 2227 1278 949
Unadjusted period prevalence (%) 0.49 0.50 0.48
Median age at first event (years) 38.40 37.38 39.77

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

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This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

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Index endpoint: K11_CD_STRICT – Crohn disease (strict definition, require KELA)

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).