ileocolitis: Ileocolitis or ileal Crohn's is the most common type of Crohn's disease. It affects both the ileum (small intestine) and the colon.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditions
|
57 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
57 |
6. Filter based on genotype QC (FinnGen only) |
55 |
Control definitions (FinnGen only)
Control exclude
K11_IBD, K11_CHOLANGI
Control conditions
not K11_CHOLANGI_STRICT
and not K11_CD_STRICT
and not K11_CD_STRICT
Extra metadata
First used in FinnGen datafreeze
DF3
Similar endpoints
↥List of similar endpoints to
Crohn's disease (strict) with PSC
based on the number of shared cases.
Similar with more cases:
- IBD (strict) with PSC
- Cholangitis (primary sclerosing, PSC), with reimbursement 202
- Cholangitis (primary sclerosing, PSC)
- Crohn disease (strict definition, require KELA)
- Crohn's disease patients in KELA-register (KELA code 209, or 208 with ICD K50)
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 159 | 66 | 91 |
| Only index persons | 154 | 65 | 89 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.00 | 0.00 | 0.00 |
| Only index persons | 0.00 | 0.00 | 0.00 |
| Median age at first event (years) | |||
| Whole population | 30.30 | 29.94 | 30.31 |
| Only index persons | 30.01 | 29.61 | 30.31 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 55 | 29 | 26 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | 30.59 | 29.19 | 32.15 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint K11_CD_STRICT_PSC and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have K11_CD_STRICT_PSC.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: K11_CD_STRICT_PSC – Crohn's disease (strict) with PSC
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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