No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
42300 |
4. Check minimum number of eventsNone |
42300 |
5. Include endpoints |
43732 |
6. Filter based on genotype QC (FinnGen only) |
42342 |
Control definitions (FinnGen only)
Control exclude
M13_SOFTTISSUE
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M70-M79
Name in latin
Morbositates textus mollis regionis deltoideae
Similar endpoints
↥List of similar endpoints to
Shoulder lesions
based on the number of shared cases.
Similar with more cases:
- Soft tissue disorders
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 310525 | 154743 | 154642 |
| Only index persons | 298030 | 150578 | 147452 |
| Unadjusted period prevalence (%) | |||
| Whole population | 4.36 | 4.43 | 4.32 |
| Only index persons | 5.58 | 5.54 | 5.63 |
| Median age at first event (years) | |||
| Whole population | 54.20 | 54.09 | 54.33 |
| Only index persons | 54.00 | 53.92 | 54.09 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 42342 | 22882 | 19460 |
| Unadjusted period prevalence (%) | 9.35 | 8.99 | 9.77 |
| Median age at first event (years) | 54.40 | 53.19 | 55.82 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint M13_SHOULDER and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_SHOULDER | 0.882 [0.81, 0.96] | 0.003 |
| Birth year | 0.992 [0.98, 1.0] | 0.06 |
During the follow-up period (1.1.1998 — 31.12.2019), 11382 out of 127682 females with M13_SHOULDER died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_SHOULDER | 0.826 [0.76, 0.89] | < 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.011 |
During the follow-up period (1.1.1998 — 31.12.2019), 16337 out of 128813 males with M13_SHOULDER died.
Mortality risk
Mortality risk for people of age
years, who have M13_SHOULDER.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.08% | 0.134% |
| 5 | 0.512% | 0.91% |
| 10 | 1.294% | 2.31% |
| 15 | 2.304% | 4.609% |
| 20 | 3.892% | 8.081% |
Relationships between endpoints
↥Index endpoint: M13_SHOULDER – Shoulder lesions
GWS hits: 4
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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