Bursitis of shoulder

M13_SHOULDERBURSITIS

Hemarthrosis: Bleeding into the joints. It may arise from trauma or spontaneously in patients with hemophilia.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M75.5
  • Hospital discharge: ICD-9 7261B
  • Cause of death: ICD-10 M75.5
  • Cause of death: ICD-9 7261B

2 out of 7 registries used, show all original rules.

861

4. Check minimum number of events

None

861

5. Include endpoints

None

861

6. Filter based on genotype QC (FinnGen only)

831

Control definitions (FinnGen only)

Control exclude M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M75
Name in latin Bursitis regionis deltoideae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 6225 3601 2591
Only index persons 5944 3456 2488
Unadjusted period prevalence (%)
Whole population 0.09 0.10 0.07
Only index persons 0.11 0.13 0.09
Median age at first event (years)
Whole population 52.66 53.18 52.04
Only index persons 52.39 52.74 51.90

-FinnGen-

Key figures

All Female Male
Number of individuals 831 518 313
Unadjusted period prevalence (%) 0.19 0.20 0.16
Median age at first event (years) 52.90 52.18 54.08

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Association

Association between endpoint M13_SHOULDERBURSITIS and mortality.

Females

Parameter HR [95% CI] p-value
M13_SHOULDERBURSITIS 1.197 [1.02, 1.41] 0.031
Birth year 0.995 [0.99, 1.0] 0.291

During the follow-up period (1.1.1998 — 31.12.2019), 318 out of 2869 females with M13_SHOULDERBURSITIS died.

Males

Parameter HR [95% CI] p-value
M13_SHOULDERBURSITIS 1.059 [0.89, 1.26] 0.509
Birth year 0.988 [0.98, 1.0] 0.011

During the follow-up period (1.1.1998 — 31.12.2019), 268 out of 2156 males with M13_SHOULDERBURSITIS died.

Mortality risk

Mortality risk for people of age

years, who have M13_SHOULDERBURSITIS.

N-year risk Females Males
1 0.093% 0.233%
5 0.725% 1.275%
10 1.765% 3.121%
15 3.525% 5.873%
20 6.049% 9.934%

Relationships between endpoints

Index endpoint: M13_SHOULDERBURSITIS – Bursitis of shoulder

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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