No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
3591 |
4. Check minimum number of eventsNone |
3591 |
5. Include endpointsNone |
3591 |
6. Filter based on genotype QC (FinnGen only) |
3450 |
Control definitions (FinnGen only)
Control exclude
M13_SOFTTISSUE
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Other shoulder lesions
based on the number of shared cases.
Similar with more cases:
- Shoulder lesions
- Soft tissue disorders
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 26065 | 14526 | 11386 |
| Only index persons | 25184 | 14177 | 11007 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.37 | 0.42 | 0.32 |
| Only index persons | 0.48 | 0.52 | 0.42 |
| Median age at first event (years) | |||
| Whole population | 50.03 | 51.17 | 48.72 |
| Only index persons | 50.00 | 51.07 | 48.63 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 3450 | 2192 | 1258 |
| Unadjusted period prevalence (%) | 0.78 | 0.86 | 0.63 |
| Median age at first event (years) | 52.43 | 51.36 | 54.30 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint M13_SHOULDERNAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_SHOULDERNAS | 1.036 [0.91, 1.18] | 0.601 |
| Birth year | 0.998 [0.99, 1.01] | 0.708 |
During the follow-up period (1.1.1998 — 31.12.2019), 1037 out of 11977 females with M13_SHOULDERNAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_SHOULDERNAS | 1.101 [0.96, 1.26] | 0.153 |
| Birth year | 0.988 [0.98, 1.0] | 0.009 |
During the follow-up period (1.1.1998 — 31.12.2019), 955 out of 9475 males with M13_SHOULDERNAS died.
Mortality risk
Mortality risk for people of age
years, who have M13_SHOULDERNAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.081% | 0.207% |
| 5 | 0.626% | 1.208% |
| 10 | 1.639% | 3.197% |
| 15 | 3.294% | 6.276% |
| 20 | 5.793% | 10.691% |
Relationships between endpoints
↥Index endpoint: M13_SHOULDERNAS – Other shoulder lesions
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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