No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
30473 |
4. Check minimum number of eventsNone |
30473 |
5. Include endpointsNone |
30473 |
6. Filter based on genotype QC (FinnGen only) |
29524 |
Control definitions (FinnGen only)
Control exclude
M13_SOFTTISSUE
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M75
Name in latin
Syndroma armillae tendinum musculorum rotatorum
Similar endpoints
↥List of similar endpoints to
Rotator cuff syndrome
based on the number of shared cases.
Similar with more cases:
- Shoulder lesions
- Soft tissue disorders
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 210716 | 100639 | 109422 |
| Only index persons | 203885 | 98531 | 105354 |
| Unadjusted period prevalence (%) | |||
| Whole population | 2.97 | 2.88 | 3.06 |
| Only index persons | 3.83 | 3.62 | 4.02 |
| Median age at first event (years) | |||
| Whole population | 55.40 | 55.35 | 55.47 |
| Only index persons | 55.29 | 55.24 | 55.34 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 29524 | 15199 | 14325 |
| Unadjusted period prevalence (%) | 6.56 | 5.97 | 7.19 |
| Median age at first event (years) | 55.64 | 54.58 | 56.77 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint M13_ROTATORCUFF and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_ROTATORCUFF | 0.809 [0.74, 0.88] | < 0.001 |
| Birth year | 0.997 [0.99, 1.0] | 0.457 |
During the follow-up period (1.1.1998 — 31.12.2019), 7812 out of 84880 females with M13_ROTATORCUFF died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_ROTATORCUFF | 0.765 [0.71, 0.83] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.009 |
During the follow-up period (1.1.1998 — 31.12.2019), 11828 out of 92350 males with M13_ROTATORCUFF died.
Mortality risk
Mortality risk for people of age
years, who have M13_ROTATORCUFF.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.08% | 0.161% |
| 5 | 0.503% | 0.941% |
| 10 | 1.275% | 2.256% |
| 15 | 2.421% | 4.175% |
| 20 | 4.348% | 7.392% |
Relationships between endpoints
↥Index endpoint: M13_ROTATORCUFF – Rotator cuff syndrome
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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