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Substance abuse

KRA_PSY_SUBSTANCE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 F10-F19
  • Hospital discharge: ICD-9 29[1-2]|30[3-5]
  • Hospital discharge: ICD-8 291|30[3-4]
  • Hospital discharge: excluded ICD-10 F10.0
  • Hospital discharge: excluded ICD-9 3050A
  • Cause of death: ICD-10 F10-F19
  • Cause of death: ICD-9 29[1-2]|30[3-5]
  • Cause of death: ICD-8 291|30[3-4]

2 out of 7 registries used, show all original rules.

26558

4. Check minimum number of events

None

26558

5. Include endpoints

28764

6. Filter based on genotype QC (FinnGen only)

27791

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 27791 10033 17758
Unadjusted period prevalence (%) 7.12 3.94 8.92
Median age at first event (years) 44.92 40.73 47.28

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: KRA_PSY_SUBSTANCE – Substance abuse

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).