No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
8803 |
4. Check minimum number of eventsNone |
8803 |
5. Include endpoints |
9322 |
6. Filter based on genotype QC (FinnGen only) |
8957 |
Control definitions (FinnGen only)
Control exclude
H7_SCLERACORNEA
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Iridocyclitis
based on the number of shared cases.
Similar with more cases:
- Disorders of sclera, cornea, iris and ciliary body
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 77858 | 40052 | 37341 |
| Only index persons | 71276 | 37106 | 34170 |
| Unadjusted period prevalence (%) | |||
| Whole population | 1.09 | 1.15 | 1.04 |
| Only index persons | 1.34 | 1.36 | 1.30 |
| Median age at first event (years) | |||
| Whole population | 47.99 | 50.82 | 44.96 |
| Only index persons | 46.93 | 49.66 | 43.97 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 8957 | 5047 | 3910 |
| Unadjusted period prevalence (%) | 1.97 | 1.98 | 1.96 |
| Median age at first event (years) | 49.62 | 48.74 | 50.76 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint H7_IRIDOCYCLITIS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_IRIDOCYCLITIS | 1.075 [0.98, 1.17] | 0.106 |
| Birth year | 0.993 [0.98, 1.0] | 0.09 |
During the follow-up period (1.1.1998 — 31.12.2019), 4114 out of 31676 females with H7_IRIDOCYCLITIS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_IRIDOCYCLITIS | 1.061 [0.97, 1.16] | 0.207 |
| Birth year | 0.986 [0.98, 1.0] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 3825 out of 28706 males with H7_IRIDOCYCLITIS died.
Mortality risk
Mortality risk for people of age
years, who have H7_IRIDOCYCLITIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.105% | 0.174% |
| 5 | 0.604% | 1.109% |
| 10 | 1.549% | 2.995% |
| 15 | 2.749% | 5.577% |
| 20 | 4.694% | 9.55% |
Relationships between endpoints
↥Index endpoint: H7_IRIDOCYCLITIS – Iridocyclitis
GWS hits: 10
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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