No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersNone 0 out of 7 registries used, show all original rules. |
0 |
4. Check minimum number of eventsNone |
0 |
5. Include endpoints |
8253 |
6. Filter based on genotype QC (FinnGen only) |
7945 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF7
Similar endpoints
↥List of similar endpoints to
Anterior Iridocyclitis
based on the number of shared cases.
Similar with more cases:
- Iridocyclitis
- Disorders of sclera, cornea, iris and ciliary body
- Autoimmune diseases
- Used for control exclusion in common control thyroid runs
- Diseases of the eye and adnexa
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 69702 | 35811 | 33500 |
| Only index persons | 63835 | 33147 | 30688 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.98 | 1.03 | 0.94 |
| Only index persons | 1.20 | 1.22 | 1.17 |
| Median age at first event (years) | |||
| Whole population | 47.40 | 50.07 | 44.53 |
| Only index persons | 46.32 | 48.94 | 43.50 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 7945 | 4471 | 3474 |
| Unadjusted period prevalence (%) | 1.75 | 1.76 | 1.74 |
| Median age at first event (years) | 48.54 | 47.48 | 49.90 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint H7_IRIDOCYC_ANTER and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_IRIDOCYC_ANTER | 1.067 [0.98, 1.16] | 0.139 |
| Birth year | 0.993 [0.99, 1.0] | 0.094 |
During the follow-up period (1.1.1998 — 31.12.2019), 3786 out of 28805 females with H7_IRIDOCYC_ANTER died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_IRIDOCYC_ANTER | 1.062 [0.97, 1.16] | 0.186 |
| Birth year | 0.987 [0.98, 1.0] | 0.006 |
During the follow-up period (1.1.1998 — 31.12.2019), 3533 out of 26180 males with H7_IRIDOCYC_ANTER died.
Mortality risk
Mortality risk for people of age
years, who have H7_IRIDOCYC_ANTER.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.077% | 0.234% |
| 5 | 0.532% | 1.173% |
| 10 | 1.501% | 2.807% |
| 15 | 2.911% | 5.503% |
| 20 | 5.054% | 9.751% |
Relationships between endpoints
↥Index endpoint: H7_IRIDOCYC_ANTER – Anterior Iridocyclitis
GWS hits: 14
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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