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Condition for Implicit Sepsis (Organ dysfunction codes)

AB1_SEPSIS_CONDITION

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D65|D695|E872|G934|I46|I959|J80|J952|J96|J960|J969|K720|K729|N00|N17|R090|R092|R400|R401|R402|R418|R55|R57
  • Hospital discharge: ICD-9 2762A|2866A|2874A|2874X|3483X|4275A|4589X|5185A|570|5722A|580|584|7800A|7802X|7855A|7855X|7991A
  • Cause of death: ICD-10 D65|D695|E872|G934|I46|I959|J80|J952|J96|J960|J969|K720|K729|N00|N17|R090|R092|R400|R401|R402|R418|R55|R57
  • Cause of death: ICD-9 2762A|2866A|2874A|2874X|3483X|4275A|4589X|5185A|570|5722A|580|584|7800A|7802X|7855A|7855X|7991A

2 out of 7 registries used, show all original rules.

50125

4. Check minimum number of events

None

50125

5. Include endpoints

None

50125

6. Filter based on genotype QC (FinnGen only)

48258

Control definitions (FinnGen only)

Extra metadata

First used in FinnGen datafreeze DF8

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 48258 22495 25763
Unadjusted period prevalence (%) 11.03 8.83 12.94
Median age at first event (years) 65.22 62.15 67.90

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: AB1_SEPSIS_CONDITION – Condition for Implicit Sepsis (Organ dysfunction codes)

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).