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Systemic lupus erythematosus, unspecified

SLE_NOS

systemic lupus erythematosus: An autoimmune multi-organ disease typically associated with vasculopathy and autoantibody production. Most patients have antinuclear antibodies (ANA). The presence of anti-dsDNA or anti-Smith antibodies are highly-specific.

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M32.9
  • Cause of death: ICD-10 M32.9

2 out of 7 registries used, show all original rules.

1021

4. Check minimum number of events

None

1021

5. Include endpoints

None

1021

6. Filter based on genotype QC (FinnGen only)

986

Control definitions (FinnGen only)

Control exclude SLE_FG

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 M32
Name in latin Lupus erythematosus disseminatus non specificatus

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 986 840 146
Unadjusted period prevalence (%) 0.29 0.33 0.07
Median age at first event (years) 48.48 47.42 54.57

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: SLE_NOS – Systemic lupus erythematosus, unspecified

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).