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Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium

DOID Endpoint Browser

O15_OEDEM_PROTUR_HYPERT

hypertension: Persistently high systemic arterial blood pressure. Based on multiple readings (blood pressure determination), hypertension is currently defined as when systolic pressure is consistently greater than 140 mm Hg or when diastolic pressure is consistently 90 mm Hg or more.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

only females

265735

2. Check conditions

None

265735

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — O10-O16
  • Hospital discharge: ICD-9 — 642
  • Hospital discharge: ICD-8 — 637
  • Cause of death: ICD-10 — O10-O16
  • Cause of death: ICD-9 — 642
  • Cause of death: ICD-8 — 637

2 out of 7 registries used, show all original rules.

20857

4. Check minimum number of events

None

20857

5. Include endpoints

21094

6. Filter based on genotype QC (FinnGen only)

20471

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF5

Similar endpoints

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List of similar endpoints to Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 20471 20471 -
Unadjusted period prevalence (%) 8.04 8.04 -
Median age at first event (years) 29.09 29.09 -

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

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This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

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Index endpoint: O15_OEDEM_PROTUR_HYPERT – Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).