No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleonly females |
265735 |
2. Check conditionsNone |
265735 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
37592 |
4. Check minimum number of eventsNone |
37592 |
5. Include endpoints
|
62562 |
6. Filter based on genotype QC (FinnGen only) |
60055 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF3
Complications of labour and delivery
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 500391 | 500391 | - |
| Only index persons | 491434 | 491434 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 14.33 | 14.33 | - |
| Only index persons | 18.07 | 18.07 | - |
| Median age at first event (years) | |||
| Whole population | - | 29.01 | - |
| Only index persons | - | 29.00 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 60055 | 60055 | - |
| Unadjusted period prevalence (%) | 23.59 | 23.59 | - |
| Median age at first event (years) | 29.25 | 29.25 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint O15_COMPLIC_LAB_DELIV and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| O15_COMPLIC_LAB_DELIV | 0.617 [0.54, 0.7] | < 0.001 |
| Birth year | 0.994 [0.98, 1.0] | 0.144 |
During the follow-up period (1.1.1998 — 31.12.2019), 1230 out of 257994 females with O15_COMPLIC_LAB_DELIV died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have O15_COMPLIC_LAB_DELIV.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.039% | No data |
| 5 | 0.357% | No data |
| 10 | 0.88% | No data |
| 15 | 1.746% | No data |
| 20 | 3.042% | No data |
Relationships between endpoints
↥Index endpoint: O15_COMPLIC_LAB_DELIV – Complications of labour and delivery
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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