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Labour and delivery complicated by umbilical cord complications

EFO MESH Endpoint Browser PheWeb

O15_LABOUR_UMBILICAL

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

only females

265735

2. Check conditions

None

265735

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — O69
  • Hospital discharge: ICD-9 — 663
  • Hospital discharge: ICD-8 — 6613
  • Cause of death: ICD-10 — O69
  • Cause of death: ICD-9 — 663
  • Cause of death: ICD-8 — 6613

2 out of 7 registries used, show all original rules.

1840

4. Check minimum number of events

None

1840

5. Include endpoints

None

1840

6. Filter based on genotype QC (FinnGen only)

1789

Control definitions (FinnGen only)

Control exclude O15_COMPLIC_LAB_DELIV

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF5
Parent code in ICD-10 O60-O75
Name in latin Labores et partus a perturbationibus funiculi umbilicalis complicati

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 15264 15264 -
Only index persons 15007 15007 -
Unadjusted period prevalence (%)
Whole population 0.44 0.44 -
Only index persons 0.55 0.55 -
Median age at first event (years)
Whole population - 29.37 -
Only index persons - 29.37 -

-FinnGen-

Key figures

All Female Male
Number of individuals 1789 1789 -
Unadjusted period prevalence (%) 0.70 0.70 -
Median age at first event (years) 29.53 29.53 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Association

Association between endpoint O15_LABOUR_UMBILICAL and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_LABOUR_UMBILICAL.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

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Index endpoint: O15_LABOUR_UMBILICAL – Labour and delivery complicated by umbilical cord complications

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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