enthesopathy: A disorder involving the attachment of a tendon or ligament to a bone [database_cross_reference: https://en.wikipedia.org/wiki/Enthesopathy]
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
11025 |
4. Check minimum number of eventsNone |
11025 |
5. Include endpoints |
13589 |
6. Filter based on genotype QC (FinnGen only) |
13102 |
Control definitions (FinnGen only)
Extra metadata
Similar endpoints
↥List of similar endpoints to Other enthesopathies based on the number of shared cases.
Similar with more cases:
- Soft tissue disorders
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 97536 | 57870 | 39147 |
Only index persons | 91332 | 55371 | 35961 |
Unadjusted period prevalence (%) | |||
Whole population | 1.43 | 1.66 | 1.09 |
Only index persons | 1.77 | 2.04 | 1.37 |
Median age at first event (years) | |||
Whole population | 46.17 | 47.28 | 44.51 |
Only index persons | 45.87 | 47.04 | 44.06 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 13102 | 8582 | 4520 |
Unadjusted period prevalence (%) | 2.99 | 3.37 | 2.27 |
Median age at first event (years) | 47.90 | 47.94 | 47.83 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint M13_ENTESOPATHYOTH and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
M13_ENTESOPATHYOTH | 0.899 [0.81, 1.0] | 0.048 |
Birth year | 0.994 [0.99, 1.0] | 0.123 |
During the follow-up period (1.1.1998 — 31.12.2019), 2038 out of 38096 females with M13_ENTESOPATHYOTH died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
M13_ENTESOPATHYOTH | 0.86 [0.78, 0.95] | 0.004 |
Birth year | 0.984 [0.98, 0.99] | 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 1759 out of 23239 males with M13_ENTESOPATHYOTH died.
Mortality risk
Mortality risk for people of age
years, who have M13_ENTESOPATHYOTH.N-year risk | Females | Males |
---|---|---|
1 | 0.079% | 0.135% |
5 | 0.467% | 0.793% |
10 | 1.142% | 2.13% |
15 | 2.323% | 4.391% |
20 | 4.154% | 7.548% |
Relationships between endpoints
↥Index endpoint: M13_ENTESOPATHYOTH – Other enthesopathies
GWS hits: 3