No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
3563 |
4. Check minimum number of eventsNone |
3563 |
5. Include endpointsNone |
3563 |
6. Filter based on genotype QC (FinnGen only) |
3446 |
Control definitions (FinnGen only)
Control exclude
M13_SOFTTISSUE
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M77
Name in latin
Metatarsalgia
Similar endpoints
↥List of similar endpoints to
Metatarsalgia
based on the number of shared cases.
Similar with more cases:
- Other enthesopathy of foot (+metatarsalgia)
- Other enthesopathies
- Soft tissue disorders
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 21498 | 15185 | 6227 |
| Only index persons | 20847 | 14870 | 5977 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.36 | 0.43 | 0.17 |
| Only index persons | 0.46 | 0.55 | 0.23 |
| Median age at first event (years) | |||
| Whole population | 53.33 | 54.03 | 51.80 |
| Only index persons | 53.50 | 54.09 | 52.02 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 3446 | 2632 | 814 |
| Unadjusted period prevalence (%) | 0.89 | 1.03 | 0.41 |
| Median age at first event (years) | 56.28 | 55.33 | 59.37 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint M13_METATARSALGIA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_METATARSALGIA | 0.893 [0.79, 1.01] | 0.071 |
| Birth year | 0.994 [0.99, 1.0] | 0.136 |
During the follow-up period (1.1.1998 — 31.12.2019), 877 out of 12519 females with M13_METATARSALGIA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_METATARSALGIA | 1.023 [0.89, 1.18] | 0.754 |
| Birth year | 0.982 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 518 out of 4990 males with M13_METATARSALGIA died.
Mortality risk
Mortality risk for people of age
years, who have M13_METATARSALGIA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.087% | 0.198% |
| 5 | 0.531% | 1.076% |
| 10 | 1.231% | 2.503% |
| 15 | 2.358% | 4.826% |
| 20 | 4.242% | 8.451% |
Relationships between endpoints
↥Index endpoint: M13_METATARSALGIA – Metatarsalgia
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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