Lateral epicondylitis

M13_LATERALEPICOND

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M77.1
  • Hospital discharge: ICD-9 7263A
  • Cause of death: ICD-10 M77.1
  • Cause of death: ICD-9 7263A

2 out of 7 registries used, show all original rules.

5483

4. Check minimum number of events

None

5483

5. Include endpoints

None

5483

6. Filter based on genotype QC (FinnGen only)

5280

Control definitions (FinnGen only)

Control exclude M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M77
Name in latin Epicondylitis lateralis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 38318 22117 16051
Only index persons 37313 21790 15523
Unadjusted period prevalence (%)
Whole population 0.55 0.63 0.45
Only index persons 0.71 0.80 0.59
Median age at first event (years)
Whole population 46.13 46.30 45.92
Only index persons 46.08 46.28 45.81

-FinnGen-

Key figures

All Female Male
Number of individuals 5280 3364 1916
Unadjusted period prevalence (%) 1.19 1.32 0.96
Median age at first event (years) 46.98 46.60 47.63

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Association

Association between endpoint M13_LATERALEPICOND and mortality.

Females

Parameter HR [95% CI] p-value
M13_LATERALEPICOND 0.79 [0.69, 0.9] < 0.001
Birth year 0.993 [0.98, 1.0] 0.132

During the follow-up period (1.1.1998 — 31.12.2019), 522 out of 16821 females with M13_LATERALEPICOND died.

Males

Parameter HR [95% CI] p-value
M13_LATERALEPICOND 0.671 [0.6, 0.75] < 0.001
Birth year 0.993 [0.98, 1.0] 0.14

During the follow-up period (1.1.1998 — 31.12.2019), 684 out of 11946 males with M13_LATERALEPICOND died.

Mortality risk

Mortality risk for people of age

years, who have M13_LATERALEPICOND.

N-year risk Females Males
1 0.066% 0.215%
5 0.431% 1.057%
10 1.13% 2.509%
15 2.097% 4.573%
20 3.698% 8.304%

Relationships between endpoints

Index endpoint: M13_LATERALEPICOND – Lateral epicondylitis

GWS hits: 3

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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