Medial epicondylitis

M13_MEDIALEPICOND

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M77.0
  • Hospital discharge: ICD-9 7263B
  • Cause of death: ICD-10 M77.0
  • Cause of death: ICD-9 7263B

2 out of 7 registries used, show all original rules.

1370

4. Check minimum number of events

None

1370

5. Include endpoints

None

1370

6. Filter based on genotype QC (FinnGen only)

1326

Control definitions (FinnGen only)

Control exclude M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 M77
Name in latin Epicondylitis medialis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 8978 5405 3533
Only index persons 8770 5322 3448
Unadjusted period prevalence (%)
Whole population 0.13 0.15 0.10
Only index persons 0.17 0.20 0.13
Median age at first event (years)
Whole population 47.80 48.29 47.07
Only index persons 47.74 48.25 46.94

-FinnGen-

Key figures

All Female Male
Number of individuals 1326 886 440
Unadjusted period prevalence (%) 0.31 0.35 0.22
Median age at first event (years) 49.22 49.66 48.34

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Association

Association between endpoint M13_MEDIALEPICOND and mortality.

Females

Parameter HR [95% CI] p-value
M13_MEDIALEPICOND 0.89 [0.74, 1.07] 0.219
Birth year 0.992 [0.98, 1.0] 0.087

During the follow-up period (1.1.1998 — 31.12.2019), 149 out of 4256 females with M13_MEDIALEPICOND died.

Males

Parameter HR [95% CI] p-value
M13_MEDIALEPICOND 0.697 [0.59, 0.83] < 0.001
Birth year 0.989 [0.98, 1.0] 0.016

During the follow-up period (1.1.1998 — 31.12.2019), 161 out of 2713 males with M13_MEDIALEPICOND died.

Mortality risk

Mortality risk for people of age

years, who have M13_MEDIALEPICOND.

N-year risk Females Males
1 0.086% 0.125%
5 0.494% 0.806%
10 1.105% 2.177%
15 1.969% 4.185%
20 3.719% 7.023%

Relationships between endpoints

Index endpoint: M13_MEDIALEPICOND – Medial epicondylitis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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