No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
564 |
4. Check minimum number of eventsNone |
564 |
5. Include endpointsNone |
564 |
6. Filter based on genotype QC (FinnGen only) |
547 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
First used in FinnGen datafreeze
DF6
Similar endpoints
↥List of similar endpoints to
Oral leukoplakia
based on the number of shared cases.
Similar with more cases:
- Oral leukoplakia, including avohilmo
- Oral leukoplakia and related diseases
- Oral leukoplakia and related diseases, including avohilmo
- Other diseases of lip and oral mucosa
- Diseases of oral cavity, salivary glands and jaws
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3606 | 1908 | 1678 |
| Only index persons | 3407 | 1821 | 1586 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.05 | 0.05 | 0.05 |
| Only index persons | 0.06 | 0.07 | 0.06 |
| Median age at first event (years) | |||
| Whole population | 58.48 | 60.03 | 56.73 |
| Only index persons | 58.24 | 59.79 | 56.47 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 547 | 297 | 250 |
| Unadjusted period prevalence (%) | 0.12 | 0.12 | 0.13 |
| Median age at first event (years) | 58.18 | 57.58 | 58.88 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint K11_ORAL_LEUCOPLACIA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_ORAL_LEUCOPLACIA | 1.137 [1.0, 1.3] | 0.059 |
| Birth year | 0.996 [0.99, 1.01] | 0.414 |
During the follow-up period (1.1.1998 — 31.12.2019), 393 out of 1808 females with K11_ORAL_LEUCOPLACIA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_ORAL_LEUCOPLACIA | 1.285 [1.12, 1.48] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.008 |
During the follow-up period (1.1.1998 — 31.12.2019), 392 out of 1574 males with K11_ORAL_LEUCOPLACIA died.
Mortality risk
Mortality risk for people of age
years, who have K11_ORAL_LEUCOPLACIA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.131% | 0.218% |
| 5 | 0.745% | 1.537% |
| 10 | 1.697% | 3.884% |
| 15 | 3.304% | 7.288% |
| 20 | 5.854% | 12.14% |
Relationships between endpoints
↥Index endpoint: K11_ORAL_LEUCOPLACIA – Oral leukoplakia
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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