No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
861 |
4. Check minimum number of eventsNone |
861 |
5. Include endpointsNone |
861 |
6. Filter based on genotype QC (FinnGen only) |
837 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
First used in FinnGen datafreeze
DF7
Similar endpoints
↥List of similar endpoints to
Oral leukoplakia, including avohilmo
based on the number of shared cases.
Similar with more cases:
- Oral leukoplakia and related diseases, including avohilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5452 | 2705 | 2719 |
| Only index persons | 5235 | 2615 | 2620 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.08 | 0.08 | 0.08 |
| Only index persons | 0.10 | 0.10 | 0.10 |
| Median age at first event (years) | |||
| Whole population | 57.42 | 59.83 | 55.09 |
| Only index persons | 57.24 | 59.67 | 54.82 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 837 | 436 | 401 |
| Unadjusted period prevalence (%) | 0.19 | 0.17 | 0.20 |
| Median age at first event (years) | 58.27 | 58.13 | 58.41 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint K11_ORAL_LEUCOPLACIA_INCLAVO and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_ORAL_LEUCOPLACIA_INCLAVO | 1.138 [0.99, 1.31] | 0.067 |
| Birth year | 0.989 [0.98, 1.0] | 0.017 |
During the follow-up period (1.1.1998 — 31.12.2019), 415 out of 2412 females with K11_ORAL_LEUCOPLACIA_INCLAVO died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_ORAL_LEUCOPLACIA_INCLAVO | 1.208 [1.05, 1.39] | 0.008 |
| Birth year | 0.987 [0.98, 1.0] | 0.012 |
During the follow-up period (1.1.1998 — 31.12.2019), 419 out of 2342 males with K11_ORAL_LEUCOPLACIA_INCLAVO died.
Mortality risk
Mortality risk for people of age
years, who have K11_ORAL_LEUCOPLACIA_INCLAVO.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.085% | 0.16% |
| 5 | 0.554% | 1.325% |
| 10 | 1.446% | 3.321% |
| 15 | 2.758% | 6.967% |
| 20 | 4.837% | 11.545% |
Relationships between endpoints
↥Index endpoint: K11_ORAL_LEUCOPLACIA_INCLAVO – Oral leukoplakia, including avohilmo
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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