No definition available.
Oral leukoplakia and related diseases, including avohilmo
K11_ORAL_LEUCOPLAC_RELAT_INCLAVO
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
3013 |
4. Check minimum number of eventsNone |
3013 |
5. Include endpointsNone |
3013 |
6. Filter based on genotype QC (FinnGen only) |
2908 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 18230 | 9927 | 8241 |
Only index persons | 17529 | 9610 | 7919 |
Unadjusted period prevalence (%) | |||
Whole population | 0.26 | 0.28 | 0.23 |
Only index persons | 0.33 | 0.35 | 0.30 |
Median age at first event (years) | |||
Whole population | 59.04 | 60.99 | 56.74 |
Only index persons | 58.93 | 60.83 | 56.62 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 2908 | 1665 | 1243 |
Unadjusted period prevalence (%) | 0.64 | 0.65 | 0.62 |
Median age at first event (years) | 60.48 | 60.15 | 60.93 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint K11_ORAL_LEUCOPLAC_RELAT_INCLAVO and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
K11_ORAL_LEUCOPLAC_RELAT_INCLAVO | 1.181 [1.06, 1.31] | 0.002 |
Birth year | 0.989 [0.98, 1.0] | 0.021 |
During the follow-up period (1.1.1998 — 31.12.2019), 1320 out of 8669 females with K11_ORAL_LEUCOPLAC_RELAT_INCLAVO died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
K11_ORAL_LEUCOPLAC_RELAT_INCLAVO | 1.233 [1.1, 1.38] | < 0.001 |
Birth year | 0.986 [0.98, 0.99] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 1182 out of 6913 males with K11_ORAL_LEUCOPLAC_RELAT_INCLAVO died.
Mortality risk
Mortality risk for people of age
years, who have K11_ORAL_LEUCOPLAC_RELAT_INCLAVO.N-year risk | Females | Males |
---|---|---|
1 | 0.103% | 0.195% |
5 | 0.575% | 1.367% |
10 | 1.485% | 3.489% |
15 | 2.861% | 6.609% |
20 | 4.837% | 11.179% |
Relationships between endpoints
↥Index endpoint: K11_ORAL_LEUCOPLAC_RELAT_INCLAVO – Oral leukoplakia and related diseases, including avohilmo
GWS hits: 1