No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
1842 |
4. Check minimum number of eventsNone |
1842 |
5. Include endpointsNone |
1842 |
6. Filter based on genotype QC (FinnGen only) |
1778 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
First used in FinnGen datafreeze
DF6
Similar endpoints
↥List of similar endpoints to
Oral leukoplakia and related diseases
based on the number of shared cases.
Similar with more cases:
- Oral leukoplakia and related diseases, including avohilmo
- Other diseases of lip and oral mucosa
- Diseases of oral cavity, salivary glands and jaws
- Gastrointestinal diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 11356 | 6396 | 4921 |
| Only index persons | 10736 | 6104 | 4632 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.16 | 0.18 | 0.14 |
| Only index persons | 0.20 | 0.22 | 0.18 |
| Median age at first event (years) | |||
| Whole population | 59.45 | 60.72 | 57.82 |
| Only index persons | 59.14 | 60.32 | 57.57 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1778 | 1034 | 744 |
| Unadjusted period prevalence (%) | 0.39 | 0.41 | 0.37 |
| Median age at first event (years) | 59.75 | 59.00 | 60.79 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint K11_ORAL_LEUCOPLAC_RELAT and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_ORAL_LEUCOPLAC_RELAT | 1.15 [1.04, 1.27] | 0.005 |
| Birth year | 0.994 [0.98, 1.0] | 0.175 |
During the follow-up period (1.1.1998 — 31.12.2019), 1192 out of 5953 females with K11_ORAL_LEUCOPLAC_RELAT died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_ORAL_LEUCOPLAC_RELAT | 1.278 [1.15, 1.42] | < 0.001 |
| Birth year | 0.994 [0.98, 1.0] | 0.25 |
During the follow-up period (1.1.1998 — 31.12.2019), 1068 out of 4459 males with K11_ORAL_LEUCOPLAC_RELAT died.
Mortality risk
Mortality risk for people of age
years, who have K11_ORAL_LEUCOPLAC_RELAT.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.089% | 0.354% |
| 5 | 0.599% | 1.888% |
| 10 | 1.725% | 4.593% |
| 15 | 3.232% | 8.523% |
| 20 | 5.64% | 14.425% |
Relationships between endpoints
↥Index endpoint: K11_ORAL_LEUCOPLAC_RELAT – Oral leukoplakia and related diseases
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data