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Crohn disease (strict definition, all UC cases excluded)

EFO Endpoint Browser

K11_CD_NOUC

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

  • K11_KELAIBD
  • and not K11_ULCER
2207

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — K50
  • Hospital discharge: ICD-9 — 555
  • Hospital discharge: ICD-8 — 5630
  • Cause of death: ICD-10 — K50
  • Cause of death: ICD-9 — 555
  • Cause of death: ICD-8 — 5630

2 out of 7 registries used, show all original rules.

1781

4. Check minimum number of events

None

1781

5. Include endpoints

None

1781

6. Filter based on genotype QC (FinnGen only)

1718

Control definitions (FinnGen only)

Control conditions not K11_KELAIBD
and not K11_ULCER

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF3
Parent code in ICD-10 K50-K52
Name in latin Morbus Crohn

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 1718 978 740
Unadjusted period prevalence (%) 0.38 0.38 0.37
Median age at first event (years) 39.74 38.30 41.65

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

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This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

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Index endpoint: K11_CD_NOUC – Crohn disease (strict definition, all UC cases excluded)

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).