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Aortic valve malfunction, age under 60 years

I9_AORTVALV_EARLY

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Pre-conditions: EVENT_AGE < 60

Registry filters:

2 out of 7 registries used, show all original rules.

3339

4. Check minimum number of events

None

3339

5. Include endpoints

None

3339

6. Filter based on genotype QC (FinnGen only)

3222

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF9

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 3222 1139 2083
Unadjusted period prevalence (%) 0.83 0.45 1.05
Median age at first event (years) 52.46 52.04 52.69

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: I9_AORTVALV_EARLY – Aortic valve malfunction, age under 60 years

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).