No definition available.
Left ventricular outflow tract obstruction, narrow definition
Q17_LVOTO_NARROW
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1631 |
4. Check minimum number of eventsNone |
1631 |
5. Include endpointsNone |
1631 |
6. Filter based on genotype QC (FinnGen only) |
1561 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Similar endpoints
↥List of similar endpoints to Left ventricular outflow tract obstruction, narrow definition based on the number of shared cases.
Similar with more cases:
- Congenital malformations of heart and great arteries
- Congenital malformations, deformations and chromosomal abnormalities
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 14391 | 5274 | 9068 |
Only index persons | 11312 | 4077 | 7235 |
Unadjusted period prevalence (%) | |||
Whole population | 0.22 | 0.15 | 0.25 |
Only index persons | 0.23 | 0.15 | 0.28 |
Median age at first event (years) | |||
Whole population | 18.56 | 15.60 | 20.08 |
Only index persons | 29.81 | 26.79 | 31.51 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 1561 | 554 | 1007 |
Unadjusted period prevalence (%) | 0.40 | 0.22 | 0.51 |
Median age at first event (years) | 47.62 | 42.34 | 50.52 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint Q17_LVOTO_NARROW and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
Q17_LVOTO_NARROW | 2.247 [1.81, 2.8] | < 0.001 |
Birth year | 0.991 [0.98, 1.0] | 0.053 |
During the follow-up period (1.1.1998 — 31.12.2019), 263 out of 3839 females with Q17_LVOTO_NARROW died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
Q17_LVOTO_NARROW | 1.537 [1.3, 1.81] | < 0.001 |
Birth year | 0.99 [0.98, 1.0] | 0.082 |
During the follow-up period (1.1.1998 — 31.12.2019), 418 out of 6581 males with Q17_LVOTO_NARROW died.
Mortality risk
Mortality risk for people of age
years, who have Q17_LVOTO_NARROW.N-year risk | Females | Males |
---|---|---|
1 | 0.212% | 0.276% |
5 | 1.202% | 1.713% |
10 | 2.968% | 4.62% |
15 | 5.465% | 8.948% |
20 | 9.766% | 15.278% |
Relationships between endpoints
↥Index endpoint: Q17_LVOTO_NARROW – Left ventricular outflow tract obstruction, narrow definition
GWS hits: -