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Degeneration of nervous system due to alcohol

ALCONEURODEGEN

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 G31.2
  • Cause of death: ICD-10 G31.2

2 out of 7 registries used, show all original rules.

721

4. Check minimum number of events

None

721

5. Include endpoints

None

721

6. Filter based on genotype QC (FinnGen only)

697

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G31
Name in latin Degeneratio systematis nervosi ex alcohol (aethylico)

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 697 112 585
Unadjusted period prevalence (%) 0.25 0.04 0.29
Median age at first event (years) 59.57 57.66 59.93

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: ALCONEURODEGEN – Degeneration of nervous system due to alcohol

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).