This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Alzheimer’s disease (Atypical or mixed)

AD_AM

Alzheimer's disease: A progressive, neurodegenerative disease characterized by loss of function and death of nerve cells in several areas of the brain leading to loss of cognitive function such as memory and language.

Suggest a new description

Endpoint definition

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Endpoint definition steps	FinnGen
Phenotype data	473681
1. Apply sex-specific rule None	473681
2. Check conditions None	473681
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — F00.24, G30.8, G30.8+F00.20 Cause of death:* ICD-10 — F00.24*, G30.8, G30.8+F00.20 2 out of 7 registries used, show all original rules.	2771
4. Check minimum number of events None	2771
5. Include endpoints None	2771
6. Filter based on genotype QC (FinnGen only)	2700

Control definitions (FinnGen only)

Control exclude G6_ALZHEIMER

Extra metadata

First used in FinnGen datafreeze DF2

NAME	AD_AM
CONTROL_EXCLUDE	G6_ALZHEIMER
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	F0024\|G308
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	F0024\|G308
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

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List of similar endpoints to Alzheimer’s disease (Atypical or mixed) based on the number of shared cases.

Similar with more cases:

Similar with less cases:

Alzheimer’s disease (Atypical or mixed)

Case counts by codes

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FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	2700	1120	1580
Unadjusted period prevalence (%)	0.65	0.44	0.79
Median age at first event (years)	81.38	81.83	81.06

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

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This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

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Index endpoint: AD_AM – Alzheimer’s disease (Atypical or mixed)

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

≡ Risteys

FG R11 + FR

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Alzheimer’s disease (Atypical or mixed)

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Alzheimer’s disease (Atypical or mixed) (AD_AM)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

Relationships between endpoints