No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
7348 |
4. Check minimum number of eventsNone |
7348 |
5. Include endpointsNone |
7348 |
6. Filter based on genotype QC (FinnGen only) |
7102 |
Control definitions (FinnGen only)
Control exclude
PAIN
Extra metadata
First used in FinnGen datafreeze
DF3
Parent code in ICD-10
K07
Name in latin
Morbositates articulationis temporomandibularis
Similar endpoints
↥List of similar endpoints to
Temporomandibular joint disorders
based on the number of shared cases.
Similar with more cases:
- Dentofacial anomalies [including malocclusion]
- Temporomandibular joint disorders, including avohilmo
- Diseases of oral cavity, salivary glands and jaws
- Pain (limb, back, neck, head abdominally)
- Gastrointestinal diseases
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 48348 | 36449 | 11702 |
| Only index persons | 47066 | 35748 | 11318 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.87 | 1.04 | 0.33 |
| Only index persons | 1.10 | 1.31 | 0.43 |
| Median age at first event (years) | |||
| Whole population | 42.71 | 42.82 | 42.47 |
| Only index persons | 42.57 | 42.69 | 42.21 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 7102 | 5732 | 1370 |
| Unadjusted period prevalence (%) | 1.95 | 2.25 | 0.69 |
| Median age at first event (years) | 46.60 | 45.55 | 51.01 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint TEMPOROMANDIB and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| TEMPOROMANDIB | 1.003 [0.9, 1.12] | 0.951 |
| Birth year | 0.989 [0.98, 1.0] | 0.012 |
During the follow-up period (1.1.1998 — 31.12.2019), 1919 out of 32533 females with TEMPOROMANDIB died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| TEMPOROMANDIB | 1.079 [0.96, 1.21] | 0.189 |
| Birth year | 0.985 [0.98, 0.99] | 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 1020 out of 10470 males with TEMPOROMANDIB died.
Mortality risk
Mortality risk for people of age
years, who have TEMPOROMANDIB.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.09% | 0.22% |
| 5 | 0.468% | 1.274% |
| 10 | 1.261% | 2.946% |
| 15 | 2.44% | 5.698% |
| 20 | 4.142% | 9.8% |
Relationships between endpoints
↥Index endpoint: TEMPOROMANDIB – Temporomandibular joint disorders
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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