No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
12783 |
4. Check minimum number of eventsNone |
12783 |
5. Include endpoints |
18517 |
6. Filter based on genotype QC (FinnGen only) |
17820 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
First used in FinnGen datafreeze
DF6
Parent code in ICD-10
K07
Name in latin
Morbositates articulationis temporomandibularis
Temporomandibular joint disorders, including avohilmo
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 125536 | 93893 | 30988 |
| Only index persons | 123206 | 92802 | 30404 |
| Unadjusted period prevalence (%) | |||
| Whole population | 2.23 | 2.69 | 0.87 |
| Only index persons | 2.86 | 3.41 | 1.16 |
| Median age at first event (years) | |||
| Whole population | 39.70 | 39.78 | 39.53 |
| Only index persons | 39.72 | 39.78 | 39.52 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 17820 | 14420 | 3400 |
| Unadjusted period prevalence (%) | 4.91 | 5.66 | 1.71 |
| Median age at first event (years) | 46.63 | 45.32 | 52.20 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint TEMPOROMANDIB_INCLAVO and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| TEMPOROMANDIB_INCLAVO | 0.827 [0.72, 0.95] | 0.009 |
| Birth year | 0.993 [0.99, 1.0] | 0.098 |
During the follow-up period (1.1.1998 — 31.12.2019), 2283 out of 74902 females with TEMPOROMANDIB_INCLAVO died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| TEMPOROMANDIB_INCLAVO | 0.923 [0.8, 1.07] | 0.29 |
| Birth year | 0.987 [0.98, 1.0] | 0.008 |
During the follow-up period (1.1.1998 — 31.12.2019), 1257 out of 24376 males with TEMPOROMANDIB_INCLAVO died.
Mortality risk
Mortality risk for people of age
years, who have TEMPOROMANDIB_INCLAVO.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.068% | 0.174% |
| 5 | 0.47% | 1.02% |
| 10 | 1.171% | 2.568% |
| 15 | 2.21% | 5.028% |
| 20 | 3.985% | 8.457% |
Relationships between endpoints
↥Index endpoint: TEMPOROMANDIB_INCLAVO – Temporomandibular joint disorders, including avohilmo
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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