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Respiratory insufficiency

RESPIRATORYINSUFF

respiratory failure: The significant impairment of gas exchange within the lungs resulting in hypoxia, hypercarbia, or both, to the extent that organ tissue perfusion is severely compromised. Causes include chronic obstructive pulmonary disease, asthma, emphysema, acute respiratory distress syndrome, pneumonia, pulmonary edema, pneumothorax, and congestive heart failure. Treatment requires intubation and mechanical ventilation until the time the lungs recover sufficient function. [NCIT:C26872]

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 J96.1
  • Cause of death: ICD-10 J96.1

2 out of 7 registries used, show all original rules.

2996

4. Check minimum number of events

None

2996

5. Include endpoints

None

2996

6. Filter based on genotype QC (FinnGen only)

2892

Control definitions (FinnGen only)

Control exclude ASTHMA_EXCL

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 J96
Name in latin Insufficientia respiratoria chronica

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 2892 968 1924
Unadjusted period prevalence (%) 0.77 0.38 0.97
Median age at first event (years) 71.84 69.11 73.21

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: RESPIRATORYINSUFF – Respiratory insufficiency

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).