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Dementia due to Parkinson's disease

PD_DEMENTIA

obsolete_dementia: ['An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.']

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Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

664

4. Check minimum number of events

None

664

5. Include endpoints

None

664

6. Filter based on genotype QC (FinnGen only)

643

Control definitions (FinnGen only)

Control exclude G6_PARKINSON

Extra metadata

First used in FinnGen datafreeze DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 643 217 426
Unadjusted period prevalence (%) 0.17 0.09 0.21
Median age at first event (years) 76.77 77.65 76.31

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: PD_DEMENTIA – Dementia due to Parkinson's disease

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).