No definition available.
Other maternal disorders predominantly related to pregnancy
EFO MESH Endpoint Browser PheWeb
O15_PREG_OTHER_MAT_DISORD
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleonly females |
265735 |
2. Check conditionsNone |
265735 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
31123 |
4. Check minimum number of eventsNone |
31123 |
5. Include endpoints |
41151 |
6. Filter based on genotype QC (FinnGen only) |
39264 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF3
Other maternal disorders predominantly related to pregnancy
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 316319 | 316319 | - |
| Only index persons | 311174 | 311174 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 9.06 | 9.06 | - |
| Only index persons | 11.44 | 11.44 | - |
| Median age at first event (years) | |||
| Whole population | - | 29.69 | - |
| Only index persons | - | 29.69 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 39264 | 39264 | - |
| Unadjusted period prevalence (%) | 15.42 | 15.42 | - |
| Median age at first event (years) | 30.00 | 30.00 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint O15_PREG_OTHER_MAT_DISORD and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| O15_PREG_OTHER_MAT_DISORD | 0.632 [0.56, 0.71] | < 0.001 |
| Birth year | 0.999 [0.99, 1.01] | 0.869 |
During the follow-up period (1.1.1998 — 31.12.2019), 1250 out of 209923 females with O15_PREG_OTHER_MAT_DISORD died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have O15_PREG_OTHER_MAT_DISORD.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.076% | No data |
| 5 | 0.441% | No data |
| 10 | 1.077% | No data |
| 15 | 2.138% | No data |
| 20 | 3.795% | No data |
Relationships between endpoints
↥Index endpoint: O15_PREG_OTHER_MAT_DISORD – Other maternal disorders predominantly related to pregnancy
GWS hits: 5
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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