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Dysplastic lesion of the vulva of unknown severity

N14_VULVAL_DYSPLASIA_NOS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

only females

265735

2. Check conditions

None

265735

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 N90.3
  • Cause of death: ICD-10 N90.3

2 out of 7 registries used, show all original rules.

39

4. Check minimum number of events

None

39

5. Include endpoints

None

39

6. Filter based on genotype QC (FinnGen only)

39

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF7

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 290 290 -
Only index persons 280 280 -
Unadjusted period prevalence (%)
Whole population 0.01 0.01 -
Only index persons 0.01 0.01 -
Median age at first event (years)
Whole population - 59.03 -
Only index persons - 58.75 -

-FinnGen-

Key figures

All Female Male
Number of individuals 39 39 -
Unadjusted period prevalence (%) 0.02 0.02 -
Median age at first event (years) 55.63 55.63 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

Association

Association between endpoint N14_VULVAL_DYSPLASIA_NOS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have N14_VULVAL_DYSPLASIA_NOS.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: N14_VULVAL_DYSPLASIA_NOS – Dysplastic lesion of the vulva of unknown severity

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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