No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleonly females |
265735 |
2. Check conditionsNone |
265735 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1414 |
4. Check minimum number of eventsNone |
1414 |
5. Include endpointsNone |
1414 |
6. Filter based on genotype QC (FinnGen only) |
1358 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
First used in FinnGen datafreeze
DF7
Similar endpoints
↥List of similar endpoints to
All dysplastic lesions of the vulva
based on the number of shared cases.
Similar with more cases:
- All dysplastic lesions of the cervix uteri, vagina or vulva
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 9508 | 9508 | - |
| Only index persons | 8975 | 8975 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.27 | 0.27 | - |
| Only index persons | 0.33 | 0.33 | - |
| Median age at first event (years) | |||
| Whole population | - | 38.96 | - |
| Only index persons | - | 38.45 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1358 | 1358 | - |
| Unadjusted period prevalence (%) | 0.53 | 0.53 | - |
| Median age at first event (years) | 39.70 | 39.70 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint N14_VULVAL_DYSPLASIA_ALL and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_VULVAL_DYSPLASIA_ALL | 1.189 [1.04, 1.36] | 0.011 |
| Birth year | 0.997 [0.99, 1.01] | 0.487 |
During the follow-up period (1.1.1998 — 31.12.2019), 561 out of 4102 females with N14_VULVAL_DYSPLASIA_ALL died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have N14_VULVAL_DYSPLASIA_ALL.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.119% | No data |
| 5 | 0.789% | No data |
| 10 | 1.98% | No data |
| 15 | 3.774% | No data |
| 20 | 6.424% | No data |
Relationships between endpoints
↥Index endpoint: N14_VULVAL_DYSPLASIA_ALL – All dysplastic lesions of the vulva
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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