No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
|
1. Apply sex-specific ruleonly females |
- |
2. Check conditions
|
- |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
- |
4. Check minimum number of eventsNone |
- |
5. Include endpointsNone |
- |
6. Filter based on genotype QC (FinnGen only)None |
- |
Control definitions (FinnGen only)
Control exclude
C3_CANCER, C3_CANCER_WIDE
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF9
Parent code in ICD-10
D07
Name in latin
Carcinoma in situ penis
Similar endpoints
↥List of similar endpoints to
Carcinoma in situ of vulva
based on the number of shared cases.
Similar with more cases:
- Carcinoma in situ of vulva
- Carcinoma in situ of other and unspecified genital organs
- Carcinoma in situ of other and unspecified genital organs
- In situ neoplasms
- In situ neoplasms
Similar with less cases:
Case counts by codes
↥FinnGen case counts by registry codes:
No upset plot: script not run.
No upset table: script not run.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 525 | 525 | - |
| Only index persons | 473 | 473 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | - |
| Only index persons | 0.02 | 0.02 | - |
| Median age at first event (years) | |||
| Whole population | - | 56.55 | - |
| Only index persons | - | 55.59 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 227 | 227 | - |
| Unadjusted period prevalence (%) | 0.09 | 0.09 | - |
| Median age at first event (years) | 57.52 | 57.52 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint CD2_INSITU_VULVA_EXALLC and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_INSITU_VULVA_EXALLC | 1.318 [1.01, 1.73] | 0.045 |
| Birth year | 0.995 [0.99, 1.0] | 0.251 |
During the follow-up period (1.1.1998 — 31.12.2019), 88 out of 377 females with CD2_INSITU_VULVA_EXALLC died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have CD2_INSITU_VULVA_EXALLC.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.11% | No data |
| 5 | 0.698% | No data |
| 10 | 1.909% | No data |
| 15 | 3.734% | No data |
| 20 | 6.473% | No data |
Relationships between endpoints
↥Index endpoint: CD2_INSITU_VULVA_EXALLC – Carcinoma in situ of vulva
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data