No definition available.
Dysplastic lesion of unknown severity in the cervix uteri, vagina or vulva
N14_FEMALE_GENITAL_DYSPLASIA_NOS
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleonly females |
265735 |
2. Check conditionsNone |
265735 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
412 |
4. Check minimum number of eventsNone |
412 |
5. Include endpointsNone |
412 |
6. Filter based on genotype QC (FinnGen only) |
399 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
First used in FinnGen datafreeze
DF7
Similar endpoints
↥List of similar endpoints to
Dysplastic lesion of unknown severity in the cervix uteri, vagina or vulva
based on the number of shared cases.
Similar with more cases:
- All dysplastic lesions of the cervix uteri, vagina or vulva
- Noninflammatory disorders of female genital tract
- Genitourinary diseases
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2793 | 2793 | - |
| Only index persons | 2743 | 2743 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.08 | 0.08 | - |
| Only index persons | 0.10 | 0.10 | - |
| Median age at first event (years) | |||
| Whole population | - | 41.62 | - |
| Only index persons | - | 41.33 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 399 | 399 | - |
| Unadjusted period prevalence (%) | 0.16 | 0.16 | - |
| Median age at first event (years) | 42.58 | 42.58 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint N14_FEMALE_GENITAL_DYSPLASIA_NOS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_FEMALE_GENITAL_DYSPLASIA_NOS | 1.288 [1.06, 1.57] | 0.012 |
| Birth year | 0.995 [0.99, 1.0] | 0.254 |
During the follow-up period (1.1.1998 — 31.12.2019), 177 out of 2382 females with N14_FEMALE_GENITAL_DYSPLASIA_NOS died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have N14_FEMALE_GENITAL_DYSPLASIA_NOS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.127% | No data |
| 5 | 0.817% | No data |
| 10 | 2.041% | No data |
| 15 | 3.893% | No data |
| 20 | 6.818% | No data |
Relationships between endpoints
↥Index endpoint: N14_FEMALE_GENITAL_DYSPLASIA_NOS – Dysplastic lesion of unknown severity in the cervix uteri, vagina or vulva
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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