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Personality disorders

DOID Endpoint Browser

KRA_PSY_PERSON

mental retardation: ['Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual is mentally retarded. IQ scores between 70 and 79 are in the borderline mentally retarded range. Scores below 67 are in the retarded range. (Joynt, Clinical Neurology, 1992, Ch55, p28)']

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

None

473681

2. Check conditions

None

473681

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — F60, F61
  • Hospital discharge: ICD-9 — 31[0|2|4]|315A|31[6-8]
  • Hospital discharge: ICD-8 — 30100|301[2-9]
  • Cause of death: ICD-10 — F60, F61
  • Cause of death: ICD-9 — 31[0|2|4]|315A|31[6-8]
  • Cause of death: ICD-8 — 30100|301[2-9]

2 out of 7 registries used, show all original rules.

12408

4. Check minimum number of events

None

12408

5. Include endpoints

None

12408

6. Filter based on genotype QC (FinnGen only)

11914

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF2

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 11914 7600 4314
Unadjusted period prevalence (%) 2.69 2.98 2.17
Median age at first event (years) 33.02 32.52 33.90

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

Mortality – FinRegistry

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This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

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Index endpoint: KRA_PSY_PERSON – Personality disorders

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).