No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
3664 |
4. Check minimum number of eventsNone |
3664 |
5. Include endpointsNone |
3664 |
6. Filter based on genotype QC (FinnGen only) |
3504 |
Control definitions (FinnGen only)
Control exclude
F5_PERSOBEH
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Other specified and unspecified personality disorders
based on the number of shared cases.
Similar with more cases:
- Specific personality disorders
- Disorders of adult personality and behaviour
- Any mental disorder
- Psychiatric diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 34444 | 16827 | 17284 |
| Only index persons | 29914 | 15563 | 14351 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.48 | 0.48 | 0.48 |
| Only index persons | 0.56 | 0.57 | 0.55 |
| Median age at first event (years) | |||
| Whole population | 32.68 | 32.52 | 32.70 |
| Only index persons | 32.06 | 32.06 | 32.06 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 3504 | 2161 | 1343 |
| Unadjusted period prevalence (%) | 0.78 | 0.85 | 0.67 |
| Median age at first event (years) | 32.96 | 32.22 | 34.15 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint F5_OTHPER and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| F5_OTHPER | 3.506 [3.11, 3.96] | < 0.001 |
| Birth year | 0.997 [0.99, 1.01] | 0.529 |
During the follow-up period (1.1.1998 — 31.12.2019), 1093 out of 12131 females with F5_OTHPER died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| F5_OTHPER | 3.73 [3.38, 4.11] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.031 |
During the follow-up period (1.1.1998 — 31.12.2019), 1763 out of 10388 males with F5_OTHPER died.
Mortality risk
Mortality risk for people of age
years, who have F5_OTHPER.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.54% | 0.647% |
| 5 | 2.22% | 4.261% |
| 10 | 5.194% | 10.378% |
| 15 | 9.909% | 19.846% |
| 20 | 17.785% | 30.119% |
Relationships between endpoints
↥Index endpoint: F5_OTHPER – Other specified and unspecified personality disorders
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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