No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1359 |
4. Check minimum number of eventsNone |
1359 |
5. Include endpointsNone |
1359 |
6. Filter based on genotype QC (FinnGen only) |
1323 |
Control definitions (FinnGen only)
Control exclude
F5_PERSOBEH
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
F60
Name in latin
Personalitas anancastica
Similar endpoints
↥List of similar endpoints to
Anankastic personality disorder
based on the number of shared cases.
Similar with more cases:
- Specific personality disorders
- Personality disorders
- Personality disorders
- Disorders of adult personality and behaviour
- Any mental disorder
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 9112 | 5724 | 3364 |
| Only index persons | 8865 | 5645 | 3220 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.14 | 0.16 | 0.09 |
| Only index persons | 0.18 | 0.21 | 0.12 |
| Median age at first event (years) | |||
| Whole population | 42.79 | 41.46 | 45.09 |
| Only index persons | 42.65 | 41.30 | 45.01 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1323 | 930 | 393 |
| Unadjusted period prevalence (%) | 0.32 | 0.37 | 0.20 |
| Median age at first event (years) | 43.73 | 42.20 | 47.36 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint F5_ANAPER and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| F5_ANAPER | 1.316 [1.11, 1.56] | 0.002 |
| Birth year | 0.996 [0.99, 1.0] | 0.366 |
During the follow-up period (1.1.1998 — 31.12.2019), 180 out of 4742 females with F5_ANAPER died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| F5_ANAPER | 1.272 [1.09, 1.48] | 0.002 |
| Birth year | 0.983 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 252 out of 2802 males with F5_ANAPER died.
Mortality risk
Mortality risk for people of age
years, who have F5_ANAPER.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.129% | 0.232% |
| 5 | 0.797% | 1.426% |
| 10 | 1.82% | 3.432% |
| 15 | 3.895% | 6.322% |
| 20 | 6.79% | 10.838% |
Relationships between endpoints
↥Index endpoint: F5_ANAPER – Anankastic personality disorder
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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