No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
3163 |
4. Check minimum number of eventsNone |
3163 |
5. Include endpointsNone |
3163 |
6. Filter based on genotype QC (FinnGen only) |
3054 |
Control definitions (FinnGen only)
Control exclude
F5_PERSOBEH
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
F60-F62
Name in latin
Perturbationes personalitatis mixtae et aliae
Similar endpoints
↥List of similar endpoints to
Mixed and other personality disorders
based on the number of shared cases.
Similar with more cases:
- Personality disorders
- Personality disorders
- Disorders of adult personality and behaviour
- Any mental disorder
- Psychiatric diseases
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 26556 | 13364 | 13054 |
| Only index persons | 24617 | 12791 | 11826 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.37 | 0.38 | 0.36 |
| Only index persons | 0.46 | 0.47 | 0.45 |
| Median age at first event (years) | |||
| Whole population | 37.74 | 38.21 | 37.24 |
| Only index persons | 37.34 | 37.82 | 36.82 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 3054 | 1860 | 1194 |
| Unadjusted period prevalence (%) | 0.68 | 0.73 | 0.60 |
| Median age at first event (years) | 38.05 | 37.45 | 38.98 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint F5_MIXPER and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| F5_MIXPER | 3.244 [2.91, 3.61] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.023 |
During the follow-up period (1.1.1998 — 31.12.2019), 1151 out of 11696 females with F5_MIXPER died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| F5_MIXPER | 3.446 [3.16, 3.75] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.028 |
During the follow-up period (1.1.1998 — 31.12.2019), 2029 out of 11097 males with F5_MIXPER died.
Mortality risk
Mortality risk for people of age
years, who have F5_MIXPER.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.314% | 0.736% |
| 5 | 1.977% | 4.649% |
| 10 | 4.048% | 10.707% |
| 15 | 7.222% | 19.512% |
| 20 | 12.506% | 31.762% |
Relationships between endpoints
↥Index endpoint: F5_MIXPER – Mixed and other personality disorders
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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